There are several different types of modifications like methylation and mainly glycosylation which include fucosylation and hexosylation, that are common to β-tubulin [54].
The concept of PTMs encompasses different types of modifications from a simple addition of atoms group such as the phosphorylation, e.g. done by Tyrosine kinase (1), to the binding of important large groups, e.g. the retinal in the bacteriorhodopsin (2).
Considering the importance of different types of modifications (cyclization, L- to D-conversion, non-natural residue, PTMs, capping of terminal residues), which are incorporated to provide therapeutic properties to the peptides, we integrated special force field libraries in PEPstrMOD to handle such peptides.
The N terminal tails of the core histones that constitute the nucleosome are subject to various different types of modifications that can influence chromatin structure and either enhance or inhibit the ability of transcription factors to bind to and regulate their target genes.
Currently, at least eight different types of modifications are known.
Five different types of modifications were applied, and all five were commonly used.
Different types of modifications occur on arginine residues, resulting in some form of antagonism since distinct types of modifications on arginines are mutually exclusive.
Employees need to be able to consider a wide range of different types of modification, but the study by Foster [ 27] concluded that managers were more likely to favour the provision of equipment, rather than adjustments to work itself that might involve changes to employment conditions.
The different mechanisms result in different types of modification patterns.
As the term mITT embraces a broad notion of trials, we will delve into how the different types of modification influence effect size.
Average effects at the ROI were quite similar between different types of modification (∼10 15% pressure relief), showing that all had relevance in optimizing the footwear.
