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Xenografting can also shed light on the differences between different types of breast cancer cells.
The notion that genetic differences lead to different types of breast cancer would have come as no surprise to a group of physicians in the 1950s, loosely called the "biologic predeterminists".
Emerging technologies such as high throughput genome mapping and microchip cDNA expression arrays may further elucidate molecular differences in these different types of breast cancer.
In addition, metabolic differences were observed between different types of breast cancer.
There were no remarkable differences in CLDN3 expression in different types of breast lesions or between normal and tumour components (Fig. 3a,b).
The present study was designed to determine whether human CLDN1, CLDN3 and CLDN4 are expressed in different types of breast lesions, what differences there are between different CLDNs in breast, and how the protein expression correlates with CLDN mRNA expression.
Alternatively, the intrinsic miRNA expression pattern may vary between different types of breast cancer, resulting in differing activation of various signaling networks.
This network analysis revealed important differences in the biological processes that distinguish these 3 different types of breast cancers and also suggested potential new therapeutic strategies.
Differences in the number of ALCAM transcripts were found in different types of breast cancer.
Gene-expression profiling studies revealed surprisingly large-scale molecular differences between ER-positive and ER-negative cancers that suggested that these two different types of breast cancers are distinct diseases [ 2- 4].
Different types of breast cancer are affecting lives of women across the world.
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