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The samples are divided by different types of alteration and sampling location as in Fig. 2 (SCR, Bastione Santa Croce; GAR, Torrione dell'Arena; CSN, Bastione Castelnuovo; FST, Torrione Venier).
Moreover, the existence of different types of alteration makes the detection of causative ones even more difficult.
A subset of variable bands representing mPing excisions or insertions, and different types of alteration in cytosine methylation patterns were excised from the dried polyacrylamide gels and re-amplified with appropriate primers.
It is not clear why the two different types of alteration generated some different phenotypes, but it is clear the NLS localization is critical for IGFBP5 function and our study showed that prevention of nuclear localization of IGFBP5 altered its function in the cells in a fashion that is consistent with in vivo clinical observation of IGFBP5.
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There are at least eight different types of alterations in histones, standing out acetylation, methylation and phosphorylation, which are the most studied (Kouzarides [2007]; Chen et al. [2010]).
It will also discuss in detail the capabilities of detecting different types of alterations by analysis of data generated by in-solution hybrid-capture and how this accommodates the clinical needs in oncology.
Query 2 > Query 3 > There are different types of alterations taking place in cancer.
In many human tumours, two different types of alterations of DNA methylation are found, termed 'hypermethylation' and 'hypomethylation'hypomethylation
To that end, the use of intuitive visualization tools that can integrate different types of alterations with clinical data is essential to the field of cancer genomics.
Thus, researchers need intuitive tools that allow the visual integration and simultaneous exploration of both different types of alterations and clinical information.
To infer MCF of different types of alterations, we apply the following strategy: i) The percentages of cells harboring the copy number abnormality (i.e. +12, del11q, del13q_x1, del13q_x2, del17p, delBIRC3, delRB1_x1, delRB1_x2) are estimated by FISH analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com