Sentence examples for different trial protocols from inspiring English sources

A total of 357 adult oncology patients were treated on 53 different trial protocols: 40 phase III, 2 randomised II/III and 11 phase II design.

We excluded pilot studies, trial protocols, trials randomising households or dyads of different individuals, short communications or conference proceedings, trials with further allocation of individuals within clusters, quasi-randomised designs, secondary analyses of trials, and trials reporting only baseline findings.

Finally, different trial designs dictate the most appropriate analysis plan and any additional relevant information that should be included in the protocol.

Table 2 summarizes trial protocols.

Among these, 106 (4.9 %) were clinical trial protocols.

Only two trial protocols were available.

The final sample comprised 52 trial protocols.

However, in these studies the treatment regimens on and off trial protocol were different.

These observations fit with expected variations in trial activity given that sites are likely to have different competing trials, different ICU admission protocols and different trials experience.

However, in order to get a correct information, it is important to consider that the methods to asses and to report the rate of responses can sometimes vary and that the definitions of the EFS and PFS may change substantially according to the protocol in different trials and may therefore introduce bias difficult to perceive in the comparative evaluation of the results [ 30, 31].

To understand whether and how rituximab affects the different pathogenetic pathways implicated in SSc, comprehensive biomarker studies should be part of the clinical trial protocol.