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The differential methylation levels of these three regions was postulated to correlate with the transcription of alternative isoforms in different tissue types, depending on the transcription start site that was unmethylated.
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For example, the greatest challenge in the analysis of microarray data is how to determine the cutoff for absent/present (AP) calls, while in EST data there is a big difference in the sizes of the cDNA libraries from different tissue types, ranging from hundreds to millions depending on the tissue.
Further, different tissue types reflect ultrasound differently.
Depending on the method for DNA introduction [ 34], different tissue types can be targeted for gene delivery, allowing increased flexibility in construct evaluations.
Recent studies have demonstrated that methylation may depend, in part, on the underlying genotype as methylation patterns from different tissue types are correlated within the same individual, and monozygotic twins show a higher rate of correlation than dizygotic twins.
Another confounding issue is that the role of mutant KRAS may further differ depending on other mutations that may be more or less prevalent among the different tissue types of origin.
The average turnover time is different for different tissue types.
However, in biomedical media, changes in the refractive index can occur between different tissue types.
Another reason could be the different tissue types investigated.
In total, we found 58 nodes present in multiple tissue types (Table 3) - 57 in two different tissue types, and one node in three different tissue types.
Patterns of incorporation were different in different tissue types.
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CEO of Professional Science Editing for Scientists @ prosciediting.com