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When outcomes are systematically different than expected to a degree where expectations cease to be meaningful, policies are never actually effective because desired outcomes are systematically never achieved.
This is a mandatory piece of contact information for all trials conducted at any international study site, and in this respect, trials involving Canadian investigators are not systematically different than any others.
Is there reason to believe that those that did not respond are systematically different than those that did respond?
These children may be systematically different than patients who are recognised and admitted urgently to the ICU.
In addition, we cannot exclude the possibility that patients who were eligible but not randomized were systematically different than trial participants.
Further, it is possible that patients who consented to the interview are systematically different than refusers in regard to their use of adherence aids.
To evaluate if participants with missing values were systematically different than cases without missing values [ 29], we evaluated means of missing values by estimation-maximization methods.
We assessed a number of scenarios where the patients who are re-randomised are systematically different than those who are not, or when patients are in different health states for each randomisation.
We found no evidence that RRs from studies using physician diagnosis to identify cases were systematically different than RRs from studies that did not identify cases in this way.
Women choosing to have an abortion after an unintended pregnancy may be systematically different than those who never had an unintended pregnancy or those who chose to carry to term.
In situations where a group of 4 households was skipped due to no available respondents, bias could have occurred if the experience of those households was systematically different than that of the households interviewed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com