Even though typical mismatch energies are of the same order of magnitude, there can be considerable differences between different substitutions at one position and between different nucleotide positions.
We described the syntheses, biological activities and QSAR studies of 36 new 5-n-substituted-2- substituted benzenesulphonyl) glutamines 6–41 with different substitutions.
On the other hand, with the different substitutions at different positions on the 2-substituted phenylacyl group, their inhibition of platelet aggregation differs.
Cation-exchanged, polyatom-substituted, and heteroatom-substituted HPAs were examined to investigate the effects of different substitutions.
However, in most of the families, there is no significant difference between bilinear multiple correlation coefficients produced by using PNI and PNS (different substitutions are measured by BLOSUM50, BLOSUM62 and BLOSUM80 matrix) (Figure 4).
For the same PT pathway position, different substitutions can have a dramatically different impact as exemplified by position E144HydA1/E282CpI.
The a priori calculated effects on different substitutions possible for a given basic system are exemplified.
Depending on the different substitutions, these amphiphiles showed different orientations in the Langmuir Blodgett films.
The effect of several single substitutions was analyzed followed by combination of up to 11 different substitutions.
Based on the experimental structures, we designed eight compounds to probe the effect of different substitutions on photophysical properties.
The photo-physical properties of all the OTES were compared and the effect of different substitutions was explicated.
