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The literature is divided on the role of these laminin-binding integrins in metastasis, with different studies indicating either pro- or antimetastatic functions.
Only Weibull models were used because the ln (−ln(Survival)) versus ln time) showed linear relations for the different studies, indicating Weibull models are appropriate [ 25].
However, in many cases, different parameter values particularly for metabolism were required for different studies, indicating significant interindividual or interexperimental variability.
Nevertheless, the findings are similar using different cut-offs in different studies, indicating that the correlation between HBL and radiologic progression is not only dependent on the particular threshold used in each study cohort.
This finding is in agreement with different studies indicating that strains with a high number of IS 6110 copies have lost genomic regions more often than strains with only few copies [ 10, 22].
But some reports revealed a small number of genes that are differentially expressed between primary and metastasis even there were discrepancies in different studies, indicating potential mechanistic importance during metastasis event [ 2- 5].
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Different studies indicated that the destructions caused by earthquakes were highly influenced by the seismic energy induced to the structure during the earthquake.
The results from across different studies indicated that 8 and 2 of 13 measured parameters exhibited a significant response by increasing or decreasing values by 25% or more in drought-stressed and in non-stressed, control plants, respectively.
Indeed, different studies indicate that the conformation of one protomer is relative to the other changes upon activation, and this has been observed in all the structural domains found in class C GPCRs (Pin and Bettler 2016).
Different studies indicated that macromolecules have access to interphase chromatin (11, 14, 32, 33).
However, the consistent performance of CRP across the different studies indicates that the findings are robust.
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