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Each stage undergoes unique epigenetic changes at different steps of disease progression in esophageal adenocarcinoma, suggesting a step-wise loss of multiple protective barriers against CpG island hypermethylation.
The biological information conveyed by mesenchymal signatures must also be considered to clarify which role(s) they might play in the different steps of disease progression.
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Exposures in the real world do not occur to single substances but to mixtures of toxicants that can interact with each other or affect different steps of multistage disease processes.
Autophagy is required for maintaining cellular homeostasis, and dysfunction at different steps of autophagy is causative in both chronic diseases, including cancers and different neurodegenerative disorders [ 23], and acute diseases, including cardiac and neuronal ischemic injuries [ 24].
We investigated the timeliness in different steps of surveillance for six relatively frequent notifiable infectious diseases in Korea.
Here, we review how the impairment of different steps of the autophagic pathway may contribute to different neurodegenerative diseases.
Given that cancer is a disease of faulty differentiation, dysregulation of EZH2-H3K27me3 involvedved in different steps of carcinogenesis.
Next, we elaborate on different steps of this algorithm.
Cen3tel cells were used at different steps of propagation reflecting different phases of transformation [23].
You integrate different steps of the examination.
Different steps of V(D J recombination can be discriminated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com