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24 Despite all known limitations, we have validated the modelling procedure in various western countries with very different smoking patterns.
Although, the model of cigarette diffusion accurately predicts the spread of smoking in most European countries (Pampel 2002), several factors suggest different smoking patterns among non-western immigrants.
By contrast although the incidence of SCLC remained higher in males than females, it declined in males and increased in females reflecting different smoking patterns that are a known risk factor for the disease.
Using a larger multicentre case control study of lung cancer in Europe, which included the above UK data (Simonato et al, 2001), we investigated whether the absolute risks of lung cancer in men are similar in other European countries with different smoking patterns and in different stages of the lung cancer epidemic.
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In this paper, we have used a novel statistical approach to provide further epidemiological insights into the relative effect of different type of smoking patterns on lung cancer.
Among women, differences in the prevalence of obesity, in tandem with different smoking, alcohol use and dietary patterns, might explain, at least in part, the variations in risk linked to geographical area.
Information on smoking patterns across different trimesters in pregnancy was not available on the vital records.
Examining prenatal smoking effects in a less developed country with different smoking epidemic and different socioeconomic patterning of smoking from Western countries may provide additional evidence bearing on its causal effect on offspring health.
The association increased even more for black women with particular patterns of polymorphisms when combined with different smoking characteristics including amount of smoking, duration, time since smoking cessation, age at smoking initiation, and being a former smoker.
However, according to our supplemental analyses, the smoking patterns of individuals who also drank heavily were actually different from smokers who drank less frequently.
For lung cancer, trends in smoking patterns explain most of the variation observed in mortality in different countries [ 30].
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