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A large coordinate separation would be expected to represent very different sets of regulatory pathways from mouse to human.
In our analysis, we found that different sets of regulatory elements were associated with this process in the CMCS cell and Cell differentiation modules.
These two distinct processes require the expression of different sets of genes and different sets of regulatory transcription factors to regulate them.
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Our findings also indicate that adult OPCs harbor a different set of regulatory miRNAs compared to mature oligodendrocytes.
As for cyproheptadine-induced G1/S arrest in Huh-7 cells, a different set of regulatory proteins may be involved.
Since no significant enrichment of alternatively spliced genes was found in the KEGG pathways, splicing may follow a different set of regulatory rules than transcription in pathways.
In addition, the fact that a different set of regulatory proteins were involved in hexane stress from those in ethanol stress implicated that variable resistance mechanisms were used by the cells for the biofuel products of different chemical properties [ 45].
A report by the Institute of International Finance, which represents more than 400 of the largest financial firms, criticized incentives provided to banks and insurers under different sets of international regulatory plans to place more emphasis on holding sovereign debt in their capital buffers.
By highlighting the interaction between different sets of actors within the regulatory realignment, we extend Oliver's (1991) (implicit) focus on the strategic responses of one class of actor during an institutional change.
In summary, the current understanding of the mechanisms underlying transcriptional noise are very much in line with our interpretation of the results presented in the paper: different promoter sequences may lead to different levels of transcriptional noise because they contain different sets of binding sites for regulatory proteins.
D-TAP differential expression was found to be predominantly condition-specific, suggesting that different sets of transcription factors orchestrate various regulatory events.
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