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These various interspecies differences imply a different predisposition of rats compared with humans to perturbations of thyroid homeostasis by chemicals that influence thyroid status (Lans et al. 1994).
Moreover, hPBMC derived from different healthy subjects show different predisposition to the activation.
The haplogroups correlate with the geographic distribution of indigenous populations and consequently with their environmental niche, and, moreover, they have different predisposition to various pathological conditions [ 4– 8].
Our results support the idea that different disease mechanisms exist in different ethnic populations [ 16], and a different predisposition gene may be involved in the IL-23/IL-23R IL-23/IL-23R IL-23/IL-23Resignalingients.
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Geneticists, though, have had difficulty identifying specific genes whose variants, known as alleles, cause different predispositions in those possessing different versions.
One of them, Terrie Moffitt, was responsible for studies that showed how different versions of the gene for one of the brain's enzymes resulted in different predispositions to criminal activity.
Chi-square analysis was performed to evaluate the existence of different predispositions to ICT positivity among subjects of the 4 categories studied.
Just like individual people, various mouse strains come in different sizes and colors, and with different predispositions to disease.
Third, serial caerulein injections can be performed in transgenic or knockout animals and will allow future studies to answer how different predispositions exert additive effects or abrogate each other, depending on the gene that is overexpressed or deleted.
Exome sequencing has shown that each subpopulation has different predispositions to various Mendelian diseases, an observation with consequences for public health planning in the context of pre-existing premarital screening programs [ 5].
This study has important implications for strategies concerning the development of drugs for the treatment of dyslipidemia and their monitoring; an example would be statins, for which different predispositions should now be taken into account for women and men.
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