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They hung off of different platforms of the carpet tree, stretching their magnificent paws out to readjust themselves and recharge, so they could prowl nobly over their kingdom.
We mapped the 170-gene set across the different platforms of the 4 datasets in study cohort 2, and despite the many technical differences among them we were able to reproduce its performance.
For our purpose, three miRNAs expression profiles were downloaded from the GEO database, which are listed in Table 4. Owing to the different platforms of the datasets, the probe sequences were mapped to the miRBase (http://www.mirbase.org) by Blast [ 24] tools for identifying the concordant miRNA names.
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While side-by-side platform comparisons for the quantification of specific metabolites are quite informative, it is also instructive to compare the different platforms on the basis of their level of metabolitle coverage.
The specificity of the different platforms of RNAi was also assessed through DNA microarrays, and the findings showed the successful development of siRNA reagents against the genes of interest and the useful application of vector-based RNAi to RAW 264.7 cells for functional studies.
Reports are beginning to appear comparing the performance of different platforms on the same tumor samples and considering the same end-points.
Special attention is given to minimum costs, minimum annoyance in the environment and maximum speech intelligibility at the different platforms of railway stations.
This difference in time scale emphasizes the importance of applying different platforms for the analysis of a complex tumor as high-grade osteosarcoma.
Therefore, the correct profiles of different platforms to the query profile might not score higher than incorrect profiles of the same platforms.
It had nothing to do with the 'sensitivity' of the different platforms; the amount of DNA that Feldmeyer et al. [ 20] used for their sample preparation (6 μg), was roughly similar to what was used in this study (5 μg).
There remain many challenges in this domain, however, with the evolution of different platforms, the complexities of normalizing miR profiling data, and the importance of evaluating sufficiently-powered training and validation cohorts.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com