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TRDV1 subgroup members are found on 4 different homology units (homology units 7, 8, 9 and 10), intercalated with different permutations of genes including members of the TRAV22, 23, 25 and 26 subgroups.
Notably, TRDV1 genes are co-located in 4 different homology units with different permutations of genes from 4 of the other massively expanded subgroups - TRAV22, 23, 25 and 26.
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Moreover, the decrease of the maximum size of the autocorrelated groups of genes (Table 2), for the different permutations of gene positions, corroborates the hypothesis of "supra-operonic" structures in Buchnera.
These tests were also applied to the Buchnera data set following different permutations of the gene positions, preserving or not the rank and the spacing between the pTU along the chromosome.
Diversity is derived from both the different permutations of V(D J genes used to form the TRA and TRB chains expressed by individual thymocytes (combinatorial diversity) and also by the activity of terminal deoxynucleotide transferase and exonuclease at the V(D J junction during recombination (junctional diversity).
The different permutations of recombined V(D J genes used to form individual IG and TR chains generate diversity (combinatorial diversity) that is further amplified by the activities of exonuclease and terminal deoxynucleotide transferase which together modify the germline nucleotide sequence at the V(D J junction (junctional diversity).
Multiplex OLA sensitivity was characterized using template DNA sequences consisting of an abridged subtype B HIV-1 Pol gene consensus and six different permutations of drug resistance mutations.
The present challenge before functional genomics is to understand how the different permutations of the same DNA binding factors alter individual gene expression.
Considering a GWAS with x cases and y controls and covering z SNPs (or g Genes), a total of x + y y = x + y ! x ! y ! different permutations of case control status are possible while up to z! (or g!) permutations of SNP significance values (or genes) can be carried out.
"We are not looking at different permutations of months to get the results we wanted".
There were different permutations of leads, of patterns, of profiles, of teams of police and outside law enforcement.
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