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The multidrug-resistant HCT-15 also showed different patterns of cell cycle histogram from the Colo 205 and HT-29.
However, two different patterns of cell cycle retardation (i.e. G0/G1 and G2/M phase growth arrests) were seen in GBM8401 and U-87MG cells, respectively (Table 1).
Recently, two different patterns of cell death were also found on two different cell animal lines after same antimicrotubular drug effects [ 3].
Several types of cancer cells such as carcinoma cells [ 21- 23], melanoma cells [ 24], lymphoma and leukemia cells (Uhlin-Hansen, L. Manuscript in preparation) have different patterns of cell surface proteoglycan expression compared to their normal counterparts.
Δ gcn5A mutants unable to induce bradyzoite-associated genes in response to alkaline stress have different patterns of cell cycle and bradyzoite gene expression from stressed wild-type parasites.
Studies by Melcher et al, utilising the suicide gene transfer system, herpes simplex virus thymidine kinase/gancyclovir (HSVtk/GCV), noted different patterns of cell death in various tumour cells.
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Leukaemic stem cells (LSCs) have stemness properties similar to those of HSCs, but they can express different patterns of cell-surface proteins: they can be CD34+CD38− cells (which are probably derived from HSCs), but they can also have CD34+CD38+, CD34−CD38+ or CD34−CD38− immunophenotypes.
Cells embedded in a 3D ECM have different patterns of cell-matrix adhesions [12] and elongated morphologies compared to 2D [18], which might give rise to different mechanotransduction mechanisms.
These changes may indicate a different pattern of cell motility once monocytes enter the endometrium.
Parallel experiments in which MEFs replaced the microglia showed a strikingly different pattern of cell migration (Fig 6B).
A concentration-dependent cytotoxicity was described [ 7], and an increase in free calcium and reactive oxygen species levels [ 15], a dysfunction of mitochondria and different pattern of cell death were found [ 17].
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