The authors decided to "look for this structures" in different pathological entities, to do so interesting specimens, were photographed, the pictures from different rotationary angles were analyzed, and the images were amplified two to three times.
Furthermore, considering these two patient groups as different pathological entities may be advised in future studies.
As described for the comedo and cribriform types of DCIS, different pathological entities can give rise to different calcification shapes.
The World Health Organization (WHO) classifies pancreatic mucin-producing cystic tumors into two different pathological entities: mucinous cystic neoplasm (MCN) and intraductal papillary mucinous neoplasm (IPMN) [ 1].
Likewise, many of the pathological data are obtained by observing the different pathological entities in longitudinal follow up of case material stored many years ago and linked with outcomes.
It has been previously shown that both histological types represent different pathological entities, since adenocarcinoma tumors have poorer prognoses, metastasize more easily to lymph nodes and are more resistant to radiotherapy than squamous cell tumors [ 32- 34].
This heterogeneity may be related to a progressive degeneration of epiphyseal cartilage, leading finally to cartilage loss and development of a thin fibrocartilage layer, or alternatively, to different pathological entities.
After segmenting the nucleolar organizer regions, we have looked at multiple individual and integrative morphological parameters in order to evaluate the possibilities of stratification of the different pathological entities.
These contrasting population frequency patterns by age for A−N+ versus A+N−, regardless how neurodegeneration was defined, strengthens our contention that A+N− and A−N+ represent different underlying pathological entities (Jack et al., 2014 b ).
Occult Hepatitis C virus (HCV) infection has been defined [1] [5] as a pathological entity displaying different clinical features from typical HCV infection.
