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The degree of clonality, therefore, can be estimated by measuring the degree of congruence between phlyogenetic trees constructed for different loci from a single genome.
We were able to identify 176 different loci from 92 different bacteria.
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DNA was isolated from two different loci for each tumor in addition to matched benign tissue from frozen radical prostatectomy specimens of three prostate cancer patients.
Two sequences (e.g., from two different loci or from two alleles at one locus) could serve as a PCR template for the generation of an enormous diversity of hybrid sequences via template switching or mismatch repair.
The polymorphism information content at different loci ranged from 0.217 to 0.825.
The number of alleles at the different loci ranged from 11 to 20 and a total of 29 allelic profiles or sequence types were recognised amongst the 66 strains.
The median expected heterozygosity (He) was 0.56, with a wide range of diversity in the different loci (ranging from 0 to 0.84) (Table 2).
Other lncRNAs act in trans by recruiting the histone-modifying enzymes to different loci away from the lncRNA transcription locus.
Linkage disequilibrium, a property that has long been of interest in population genetics, is "nonrandom" association of alleles at different loci resulting from shared histories of mutation and recombination.
The frequency of null alleles in the different loci ranged from moderately low (<0.10; RhB107, RhC112, RhD212, RhD2 and RhB2) to high (≥0.20; RhA112, RhA212, Rhandand RhC2) values (Table S1).
Statistically, epistasis refers to interaction between variants at multiple loci in which the total effect of the combination of variants at the different loci may differ considerably from a linear combination of the effects of individual loci.
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