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In this way, if these different levels of regulator activity yield significantly different target expression measures, one might assume that the regulator is actually acting on the target.
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In order to solve this problem, the bottom of young leaves of date palm offshoots were cultured on eight different nutrient media with different levels of growth regulators (Anjarne and Zaid, 1993).
These differences in tamoxifen action have been attributed to the different levels of transcriptional co-regulators present in breast and endometrium cells.
This latter point may relate to different levels of key upstream regulators of IKK.
Their strategic coastal domains revealed different levels of economic productivity, contextual issues and regulator-operator environment.
Different levels of expression and roles for these regulators have been reported in a variety of invasive carcinomas.
Since different cell types may have different levels of protein expression for each co-regulator, the overall balance of co-regulatory proteins with activating and repressing activity may determine whether tamoxifen has an estrogenic or anti-estrogenic effect.
One important regulator controlling all different levels of gene expression is the multi-subunit CCR4-NOT complex.
Sirtuins are important regulators of mammalian physiology and have different levels of NAD+-dependent protein deacetylase activity.
The Sprouty proteins are currently recognized as key regulators of ERK signaling that act on different levels of the pathway.
These transcriptional regulators can affect gene expression levels at different levels of RNA metabolism, such as controlling the formation of the exon junction complex, the export of mRNA through the nuclear complex and translation initiation [ 36, 52, 53].
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