Sentence examples for different gene expression profiling from inspiring English sources
Five different gene expression profiling datasets on breast cancers were analyzed in this study.
Several reviews have pointed to the limited gene overlap found between gene signatures previously identified in different gene expression profiling studies of tumors of the respiratory tract 10, 25, 26, 61.
Data from five different gene expression profiling experiments outlined above, using three different inkjet printed Agilent 60-mer array designs in a 2-color format and SYBR Green qPCR, were analyzed both individually and combined to form a single large data set (Table 1).
Poor reproducibility may be due to the use of different gene expression profiling methods or platforms, tissue of different origin, methods used for biological sample preparation, time of tissue collection at pre-symptomatic or symptomatic stage, and use of a particular batch of rodents or human cohort.
We have also identified from our sequences a very high expression of the cancer-associated MALAT1 ncRNA and we replicated this observation in two different gene expression profiling experiments of well-annotated ER+ breast cancer patient cohorts, finding also an high variance between Tamoxifen treated and untreated patient samples.
For interclass, unpaired comparisons, we used a two-tailed Student's t-test with equal variance to identify differences in expression (log (base 2) transformed) of individual gene from different gene expression profiling studies (for each of four normalization methods namely MAS5.0, GC-RMA, PLIER and RMA discretely).
In fact, recent transcriptional analysis of tumor-derived Treg cells shows that they express a different gene expression profile than Treg cells in healthy mice [58].
For instance, genes up-regulated experimentally by Myc, c-Src, ERBB2, or Akt were co-expressed in at least three of four different gene expression profile datasets of human PCa (representing approximately 250 patients in all).
Both seasonal patterns involved large numbers of genes that were highly expressed relative to background, yet each produced very different gene expression profiles.
Some genes expressed following administration of tPA interacted with ischemic stroke, with a different gene expression profile for tPA in rats with middle cerebral artery occlusion (MCAO) followed by reperfusion compared to rats with permanent-MCAO.
