However, response-shift literature warns us not to be overly optimistic, as no variables have been identified that consistently moderate different degrees of response-shift [ 5].
Our finding showed that there were different degree of responses to 2-year and 10-year design storms but the general patterns and insights deduced were similar.
Although susceptibility for presenting an adverse clinical course (i.e., sepsis, septic shock, multiples organ failure, or death) varies due to different degrees of inflammatory response [ 30], genetic factors of the host may influence the nature and intensity of this response.
This study provides evidence that antigens prepared from genotypically distinct strains of L. braziliensis induce different degrees of immune response.
Several factors influence the outcome of critically ill patients, including different degrees of inflammatory response to infections and genetic factors [ 3].
In addition, our previous studies have shown that the efficiency of DNA repair in PBMCs of MM patients could prospectively distinguish between patients with different degrees of therapeutic response, providing the basis for pre-screening and selection of those patients more likely to benefit from this treatment (Souliotis et al, 2003; Dimopoulos et al, 2005, 2007; Stefanou et al, 2012).
Moreover, when related to different degrees of ACR response, the results obtained using CDAI were graded with statistically significant and clinically meaningful differences between all group means, and were very similar to those seen for the respective DAS28 and SDAI groups.
The SA was then used to test new artificial tear formulations supplemented with silver ions as an active constituent, showing different degrees of inflammatory responses as indicated by the migration of MPO and F4/80 positive cells towards the epithelium.
Differences in polymorphism-associated TLR2 may influence the recognition of pathogens, which could cause the different degrees of the host response [ 34].
