We also repeated the analysis with a different definition of done as either a tick mark on the patient's chart or a result within 4 weeks.
The four different definitions of falls did not interfere with the main results of this study.
Use of different definitions of variable sites does not alter this conclusion (see Materials and Methods and fig. 2 c and d).
In our study, the within patient estimates, based on different definitions of treatment status, did not invalidate the results from the main analyses, indicating that exposure time misclassification is unlikely to account for the results.
The results of the current study provide evidence that tegaserod does not increase the risk of either abdominal surgery or gallbladder surgery (including cholecystectomy), a finding that was consistently observed under different definitions of exposure, and did not appear to be confounded by any baseline differences of the tegaserod initiators.
The difference simply reflects different definitions of occurrence rates, and does not signify inconsistency.
This finding was consistently observed under different definitions of exposure to tegaserod and did not appear to be confounded by baseline imbalances between tegaserod initiators and their comparators.
In one study published in 2006, Dahlsrud identified and analyzed 37 different definitions of CSR and his study did not capture all of them (Dahlsrud 2006).
So far, most studies on double FIT sampling either did not perform colonoscopy in FIT negative individuals [ 15, 16], did not evaluate different definitions of positivity for double FIT sampling [ 14, 17, 19], or did not assess the effect of different cut-off values [ 17, 20].
The different definitions of household income categories make it difficult to do a comparative interpretation of our results, and to establish the generalizability of the association between household income and NVP.
The analysis in this study was conducted with four different definitions of falls, and the different definitions did not alter the main results of our study.
