Despite a growing number of reported positive genotype phenotype associations across a variety of different diseases, a substantial proportion of these associations lose significance when tested in different patient populations, casting doubt on whether the association truly exists or merely represents a chance finding [ 7].
It is clear, however, that for different reasons, a substantial number of patients had lesser benefits from such intensive treatment.
Besides heterogeneity in patient populations and treatments between different studies, a substantial reason for the observed variation might be attributable to an inadequate use of statistical methods (Simon and Altman, 1994).
This role play was interpreted differently by different persons with a substantial number also identifying with it.
While substantial differences may be noted between different demographic subgroups, a substantial proportion (> 20%) of each subgroup reported a score greater than the cut-score.
But it might provoke nostalgia of a different kind, being a substantial entry in a genre, the microcosmic portrait of an age, at which English novelists used to thrive.
The guts of different individuals have a substantial overlap in terms of species composition and function because it was always thought that human gut flora was very variable".
Whenever required, by the same route and on the same growing granule, a multiple, alternate and cyclic as well as continuous polymerization can be obtained which attains the most complete and intimate mixing of different polymers, giving a substantial "homogeneity" of the final polymer.
Our contribution of 3215 different 3' ESTs is a substantial expansion of the number of marmoset sequences.
Each core set contained wild and cultivated accessions from the different groups, and a substantial fraction of putative hybrids.
