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Differences within the coding regions were not identified.
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For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties.
We also obtained evidence for a novel HML-2 type II-like allele that displays several nucleotide differences within the Rec coding sequence.
The constant comparative method enabled us to identify similarities and differences within the data coded to the same and different subthemes from parents and clinicians.
NV-Tambun differed from all known NV at 47 nucleotide positions; 28 of these differences occurred within the virus coding regions.
This analysis revealed 19 nucleotide differences between the two cDNAs within the coding region, ten of which result in amino acid substitutions (Figure 2A; Figure S2).
HLA-B exhibited the highest number of nucleotide differences within PBR coding exons, with up to 51 nucleotides diverging between alleles, followed by HLA-A, -DRB1 and -DQB1 alleles (up to 38 diverging nucleotides), and HLA-DQA1 (34), -Cw (27) and -DPB1 (20).
These differences between isolates are evidence of gene recombination that has occurred within the coding and gene-flanking regions.
Most of the size variation is due to differences in the control region, although some of the genomes have additional noncoding regions within the coding region.
Within the coding region examined (E9L-A24R), there is only one nucleotide difference between the two isolates that is predicted to result in an amino acid change.
Several genes also had additional TSSs within the coding region.
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