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Most striking is the dramatic difference in the titration profiles between the two inhibitors.
There is very little difference between the titration curves in 100 mM KCl and 100 mM NaCl, as reported for KR2.
Although there were differences in the shape of the titration curves, the normalized curves showed that humic acids of different sources can exhibit common similarities.
The differences in intermolecular NOE patterns between HMA and rimantadine are consistent with the differences in NMR titration data between the two inhibitors shown in Fig. 1A.
Higher tidal volume (10 ml/kg) leading to higher mean airway pressure, the termination criteria used in our study, and the differences in titration technique (based on oxygenation versus pressure volume curve) may account for this difference.
The traces offer insight into the relative binding affinities as clear differences in the amount of complex formed across the titrations are observed.
deviation and 'S' is the incline in the titration curve.
The differences in the patterns of the residue chemical shifts for this titration indicate substantial differences between the conformations of loop 6 for the wild-type and L6RM enzymes.
Meanwhile, we have presented the spectral and concentration profiles for each species in the titration process.
Buffer blanks were also included in the titration series.
The twenty seven remaining rats participated in the titration study.
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