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These estimates were based on different methodologies but the wide variation observed could also be explained by differences in the screening setting (opportunistic or population based with quality standards) and in the cohort of women analyzed.
These differences in the screening performance are attributable to multiple factors, such as the different selection of: (a) the protonation/tautomerization state of the target's binding site residues and molecules of the datasets, and (b) the input geometry of the prepared molecules due to the intrinsic differences between the force field parameters of both preparation schemes.
The differences in the rates of depression, anxiety and stress symptoms between our study and others may be attributed to differences in the screening or diagnostic instruments used, the socio-cultural differences of different populations and also the sample size of the subjects.
"It isn't clear exactly at which age women should begin screening," Nunn added, "which is why there are differences in the screening programmes across the UK".
Such mutant pairs with discrepancy in their interaction scores may be either due to differences in the screening approaches or due to false positive findings.
Among these jurisdictions we do not consider that small differences in the screening programmes explain differences in the stage distribution or in stage-specific survival.
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Differences in the screen capabilities and quality are potentially a much larger issue.
While the events in this episode follow the book, differences in the screen adaptation include not introducing the council's delegation with Ser Barristan and Lord Renly and the conversation between Robert and Eddard taking place during breakfast instead of on horseback.
The major steps in an analysis involve processing the raw sequence reads, assessing the data quality and determining representational differences in the screen in a statistically rigorous way.
We believe the differences in the screen results largely stem from methodological and technical differences (see Additional file 1, Table S4).
Interestingly, only Smarcad1 was identified in both screens, which could be due to inherent differences in the screen designs, including cell type (ES cell versus C2C12 muscle cell), form of mutagenesis (gene trap versus RNAi), inherent non-saturating nature of the screens and thresholds for the reproducible change in marker fluorescence.
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