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Studies by the Rand Corporation in the 1980s identified substantial differences in the scale-up and start-up performance of plants processing particles versus those processing liquids or gases.
But the scale up requires support.
Despite differences in the details, all of the SCALE-UP rooms were designed to facilitate peer-peer and peer-instructor interaction and many mentioned this explicitly as a helpful feature.
qPCR supported the results of macroarray experiments for vitellogenin, apolipoprotein, and nasp, with differences only in the scale of estimated up-regulation or down-regulation and the significance of the effect of treatment; macroarrays underestimated effects compared with qPCR results.
Note the difference in the scale in the yolk sac.
The shift from cups to buckets is a difference in the scale of the financial impact.
This difference however can be tolerated since the scale-up factor was at 40 times in terms of cultivation volume.
This increases to US$ 14.86 per MARA (range US$ 14.37 to 21.28) in the projected scale up; the difference is due to the smaller target population per clinic, on average, in the non-pilot sites.
The same story is told around the world, the only difference being in the scale of violence.
The differences between the scale items are in fact by design.
To explore the effect of morphology on observed AgOr expression, we have attempted to normalize sex-specific differences in transcript abundance by scaling up male AgOrs in proportion to the number of female chemosensilla.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com