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Furthermore, the key enzyme of methanol utilization, AOX1, was differently regulated in the two strains and indicated significant differences in the regulation of energy metabolism.
Remarkably, the integration of data from three different levels allowed for the identification of differences in the regulation of the core metabolism between P. pastoris and S. cerevisiae.
Differences in the regulation of secretion between the different cell types with reduced/absent levels of REP-1 could explain the tissue specific degeneration that occurs in choroideremia.
The scenarios above are further complicated by differences in the regulation of Perforin-2 in different cells.
These results indicate differences in the regulation of genes located in different isochore families, a point of functional and evolutionary relevance.
However, there are also differences in the regulation of cell surface genes and of transcriptional regulators during hyphal growth between both species as well.
Whether, there are differences in the regulation of Hsp90 ATPase activity by different client proteins remains to be seen.
Overall, we note large-scale differences in the regulation of regulons as determined by different sets of putative transcription factors in these species.
In some instances, differences in the regulation of Brachyury expression are observed between different regions of the notochord in the same animal.
Our discovery of orthologous CREs with different dynamic methylation potential amongst mammals may help to uncover important differences in the regulation of orthologous CREB target genes relevant to human development and disease.
WASHINGTON -- Republicans thwarted the Democrats' efforts to overhaul financial regulation for a second day on Tuesday and floated an alternative proposal with some crucial differences in the regulation of consumer lending.
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