In every experiment we utilized mature DCs and compared CD4 T cell lines to the TZM.bl cells as the recipients, to control for donor specific-differences (in the recipient cells) and the data shown are representative of both co-culture methods.
However in reality, the genetic relationship between pairs of GIAs is not perfect because genetic diversity between such pairs originates from several genetic factors such as the difference in the recipient cytoplasm, mutations in the somatic cell and gene imprinting in the nucleus of the somatic cell [ 8- 10].
There was no difference in the recipient- derived CD45.2+ KLS cell (Fig. 4E).
We observed no differences in reconstitution of the recipient mice with NK cells from different backgrounds suggesting no difference in trafficking and survival of the transferred cells.
However, differences were noted in the recipient age distribution and diagnosis, and the geographic location of the transplant center.
In addition, there was no significant difference in any of the recipient factors or short-term outcomes in terms of 3 and 12 month serum creatinine between the two groups (Table 2).
Gordon Gekko, character in Wall Street (feature film, 1987)"If all the money and property in the world were divided up equally at, say, three o'clock in the afternoon, by 3.30 there would be notable differences in the financial condition of the recipients.
Of the 20 AA differences that had rapidly reverted in the recipient, 14 (70%) were in donor-HLA-restricted epitopes and equally distributed over Gag, Env, and Nef genes.
Inconsistency in the conferral of benefit may be due to differences in the immunological constituents passed to the recipient infant.
We believe that the difference in gender between the recipients in the studies using PLTP deficient mice is not a likely explanation for the conflicting results.
However, our multivariable analyses did control for baseline differences in the care needs level of the recipients.
