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Nevertheless, distinct differences in the receptor binding sites allow for high specificity between ligands.
Our results suggest that the activity of ABC transporters, such as P-gp, as well as possible species differences in the receptor affinity of radioligands, are important factors to consider in the design of preclinical PET studies.
The number of PGP 9.5 positive fibers per section was significantly higher in the microbiopsies of healthy women than in traditional biopsies from the healthy women (Table 4), but there were no significant differences in the receptor expression between the two biopsy techniques.
It appears possible that phosphatidyl serine receptor-mediated actions as assayed using the ZIP code identification may allow detection of differences in the receptor density based upon source of the endothelial cells and thus differences of EV adherence to those cells.
Differences in the receptor variables, pgr and er, may be due to variation in the methods of measurement.
Differences in the receptor isoform expression profiles may be critical to understanding the role of PRL in mammary tumorigenesis.
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Accurate free energy calculations on mutated ligands provide differences in the receptor-ligand binding affinity, thus offering a direct, quantitative comparison to experiment.
Amino acids at the receptor-binding sites of the HA1 protein are associated with the differences in the receptor-binding specificity [13].
Together these observations suggest that there are intrinsic differences in the receptors that activate these two sets of proteins, and that these differences are independent of tissue of origin, transformation, or receptor expression level.
There were no significant differences in the receptors concentration between all investigated groups (Table 2).
They may also be related to differences in the receptors for octopamine, tyramine, or both [ 28],[ 29], as isC females increased oviposition significantly after injection with octopamine.
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