There was no difference in the Predisposition, Infection, Response, and Organ dysfunction (PIRO) score between groups (6.4 vs. 5.7, P = 0.052).
However, there is evidence that autosomal genes may contribute to sex differences in the genetic predisposition to psychiatric phenotypes [ 3].
However, it is possible that some parents of the present study subjects have avoided working in a farm environment due to respiratory problems, which could lead to differences in the genetic predisposition between those living and those not living on a farm in infancy.
While differences in genetic predisposition of the population and gluten consumption could explain part of the differences in celiac disease occurrence [ 10], the complex and changing pattern of its occurrence indicates that environmental factors, besides gluten, affect celiac disease development.
The differences in breed predisposition clearly indicate a genetic influence on canine mammary tumour (CMT) development.
This disparity could be due to differences in genetic predisposition between the two populations, further study is required to establish it.
Thus, our hypothesis is that metabolic differences are more important than cytokine differences for the predisposition to capillary leak syndrome in allotransplant recipients.
We strongly believe that the ethnic differences in the nature of genetic predisposition to different complex genetic disorders could also lead to inconsistency in the pattern of association in our population, as has also been reported earlier with reference to other complex disorders in the Indian populations [25].
Considering differences in genetic predisposition between populations and the important role of VEGF gene in the angiogenesis during the pregnancy, we conducted a case-control study, to test the association between the rs699947, rs1570360, rs2010963, and rs25648 VEGF genetic variants and PE.
It also acted as a trigger to disclose individual differences for the predisposition to vary the response to CO2.
