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Such differences in the pathogenicity of animal and human pathogens are known and are thought to be due to the differences in virulence as result of differential gene expression [1].
There are significant differences in the pathogenicity and course of disease among different serotypes, and infection of certain serotypes can persist for years in immune competent individuals [1], [4], [31].
We present here the complete genome sequence of S. flexneri 5b Sf8401 and a comparison with the S. flexneri 2a Sf301 genome, which reveals differences in the pathogenicity islands and chromosomal rearrangements between different serotypes of this species.
To determine pathogenicity, we inoculated 2-week-old domestic ducks intranasally with H5N8 viruses in groups of 3. The H5N8 viruses were moderately pathogenic (0%20%% mortality rate), and there were no differences in the pathogenicity of the 3 viruses tested.
There were no differences in the pathogenicity of the 3 H5N8 viruses found in South Korea, and they were less pathogenic (0%20%% mortality rate) than previous H5N1 viruses in South Korea that caused outbreaks in 2008 and 2010 (50%100%% mortality rate) (10, 12, 25 ).
The clinical importance of genotype-related differences in the pathogenicity of HBV has been revealed recently.
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It also underscores the importance of understanding the innate immunity of the insect host in providing insights into the mechanisms underlying the difference in the pathogenicity level of different fungal strains in these insect models.
The difference in the pathogenicity of these viruses are encoded in the structure of the expressed proteins, and the design of drugs and vaccines to counter virulence should take these differences into account.
Moreover, it is not clear whether differences exist in the pathogenicity of these two species [ 18].
Comparative genomics has been widely used to explain differences in the lifestyle and pathogenicity of different bacteria, ranging from Burkholderia [ 1] to Yersinia [ 2].
The difference in the observed pathogenicity of conidiation color mutants in these different host models is most likely attributed to the difference in host immune responses induced by the color mutants.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com