There are some differences in the motifs in the two types of FAST proteins.
However, there were some differences in the motifs contained in NS22 and NS16.
The distances between BSP A, BSP B and BSP C, which represent differences in the motifs in their promoter regions, could result from unequal recombination combined with diversifying selection [ 51].
In some cases, differences in the motifs obtained from related C2H2 TFs can be rationalized: Figure 5 (right) shows the example of paralogs EGRH-1 and EGRH-3, in which the motifs obtained by PBM closely reflect those predicted by the recognition code, which differ at several positions.
This difference in the motif pattern might imply a functional difference between PBPs and GOBPs.
We found a significant difference in the motif counts and the conservation ratio of the motif modes with and without the randomization of the GO annotations (p <= 0.0001; see additional file 1-Table S6).
Comparison with the previously reported structures revealed that our structures adopt basically identical fold but display significant differences in the wing motif, which could account for the difference of PTM patterns between HSF1 and HSF2 (Anckar et al., 2006, Jaeger et al., 2016).
In future it will be important to explore how ubiquitylation of WNK isoforms by CRL3KLHL3 is regulated and whether differences in the degron motif sequence might have an impact on the regulation.
Again, we found high significant differences in the overall motif distribution within the tRNA SINE clone sequence (P <.0001) and in pairwise comparisons among the different regions: poly-Y, A-rich tail and other parts (all three comparisons yielded a P <.0001).
Fourier transform ion cyclotron resonance mass spectrometry reveals substantial differences in the structural motifs of lignite and leonardite humates, which can be used for the standardization and molecular systematics of humic substances and for the directed design of humate-based products.
