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To find statistically significant differences in the modification levels between the GFL and the OL tissues, a binomial analysis was performed with Bonferroni-corrected p-value of 0.05 as a cutoff.
Statistically significant differences in the modification levels between all the five neuronal tissues were detected using a binomial analysis with Bonferroni-corrected p-value of 0.05 as a cutoff.
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Studies of circular dichroism (CD), electrophoretic mobility (EM) in agarose gel and atomic force microscopy (AFM) showed differences in the modifications caused by the three complexes on DNA.
The points lie near the 45° line of unity, indicating no significant difference in the modification of VOR gain by motor learning in the P/Q mutants as compared with wild-type (F2, 299 = 0.558, p>0.50, ANOVA).
Molecular dynamics simulations were used to investigate possible explanations for experimentally observed differences in the growth modification of calcite particles by two organic additives, polyacrylic acid (PAA) and polyaspartic acid (p-ASP).
However, it has been reported that there are differences in the epigenetic modification and expression of genes between iPSCs and ESCs and the expression of exogenous pluripotent factors is likely to cause tumors (Okita et al., 2007; Bock et al., 2011; Menendez et al., 2011).
Similar to our data, fragment lengths were dependent upon the recipient strain used, and this was thought to be due to differences in the restriction modification systems [11].
We hypothesized that the consequence of a functional SNP sometimes can be seen as a differences in the histone modification level, due to changes in TF binding or nucleosome positioning.
Moreover, other limitations are that physical/sexual IPV and emotional IPV were aggregated into one variable for the purpose of multivariate analysis due to relatively small numbers, and that the sample size may not have been sufficient for detecting differences in the effect modification analyses.
Detection of these variants suggests a difference exists in the modification states of these tRNAs for the sample analyzed as compared to those already catalogued in the modified tRNA databases.
This 'genetic variation' can lead to differences in the chemical modifications that occur to DNA, which is known as epigenetic variation.
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