These differences persisted in the lab over several generations, demonstrating a genetic basis.
"There are fundamental differences in the way labs are run," says Guusje Bonnema of Wageningen University in the Netherlands, and this can make collaboration difficult.
Obtained differences in the number of LAB between the dry fermented loins without (control-P0) and with the addition of Lb. rhamnosus LOCK900 (P1 and P2) indicated a good growth of probiotic strain during three weeks of ripening process and good survival for all time during storage.
To determine if the differences in initial lab data (Table 3) between the progressors and non-progressors at the time of entry to stage 3 was predictive of progression, we used classification algorithms, generated from the training set, on the initial data (testing set).
The authors need to make explicit all the various differences in the experiments (sites, labs, equipment), and then they can use this as a 'strength' as they argue in their rebuttal.
The incoherent genes may also reflect differences in the conditions that the labs use to grow cells.
It is important to confirm the differences in metabolic lab values between progressors and non-progressors and to validate the classification models with a larger set of patients.
Other differences affect daily life in the lab, especially norms concerning authority, originality, individuality, and manner of communication.
Mean differences between the groups in the lab exercise scores were assessed using independent samples t-test.
