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During the first 10 min of the internalization period, there were no significant differences in the internalized GluR2 between the Tmub1/HOPS-RNAi-transfected and scramble-transfected neurons (n = 12, P>0.05; t-test; Figure 5B).
Differences in total observed tumor activity can be explained primarily by differences in the internalized portion of injected dose while surface binding curves remain nearly identical across radiolabels.
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The MGCs were evidently specialized for phagocytosis of large targets, but this was not simply a function of the larger cell size: with 20-μm beads, there was no significant difference in the internalized bead/nucleus ratio between MGCs with 3 9, 10 19, 20 29, and ≥30 nuclei, demonstrating that phagocytosis of these large particles by MGCs was independent of cell size.
The upper panel of Fig. 5 shows the differences in the concentrations of internalized LDL in the two cases.
In temperature-shift and acid washing studies with G-CSFR mutants containing either single or double leucine to alanine substitutions at residues 753 and 754, no significant differences in internalized ligand were observed between the WT and L→A transfectants (Figure 2).
First of all, in this study, like in others [ 55], a large difference in the number of internalized objects from cell to cell was observed.
Quantification of mycobacteria within a total of 293 random macrophages (3 pooled experiments) revealed no difference in the number of internalized M. marinum 14 (0-93) vs 17 0-811); p = 0.19) between Cd36 +/+ and Cd36 -/- macrophages.
In this study we investigated differences in trafficking of internalized oxLDL and oxLDL-IC using fluorescently labeled lipoprotein moieties.
The model also enabled the evaluation of the "residence" of the radioisotope in the tumor, particularly in the internalized compartment.
Early time points show similarity in the activity in the internalized compartment for both radiolabeled forms of J591.
The items in the internalized homonegativity scale were found to be reliable within the subsample (α = .9).9
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