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Thus, patient 11 expressed two transcripts with the same IGHV, IGHD and IGHJ genes and therefore identical HCDR3s, but had differences in the Ig HC V region somatic mutations.
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Inner-group comparisons resulted in step directions with significance and step directions with a trend to significance in pre/post-differences in the IG for INI, foot off, and foot contact (Table 3).
Differences in the changes between IG and CG were tested with interaction terms between the group and measurement.
Differences in the changes between IG and CG were found in depression (p = 0.017) and distress (p = 0.029) and marginal differences in usual activities (p = 0.058) and sexual activity (p = 0.051) among men (additional file 2).
There were no significant differences in the baseline characteristics between the IG and the CG.
There are, however, some subtle differences in the relative orientations of the Ig and LRR domains between the three NGL family members (Supplementary Figure S4).
No significant differences were observed with regard to the concentrations of IgA (P= 0·236) and IgM (P= 0·062) in the bile of piglets; however, Base piglets tended (P≤ 0·089) to have a lower concentration of IgM when compared with piglets from the other treatment groups.> -wrap-foot> There were no significant differences in the plasma concentrations of Ig among the treatment groups.
Based on adjusted costs there were only two statistically significant differences in the cost categories between IG and CG: The intervention was associated with higher costs for informal care (+4,968 EUR; p =0.03) and for outpatient physician services (+406 EUR; p = 0.03) (Table 4).
Although both groups showed a reduction in BMI directly after the trial and at 12 months follow-up, no significant differences between the IG and UCG were found.
Despite some differences in the immunologic effects of TACI-Ig and BAFF-R-Ig, both reagents delay disease onset and death by 4 5 months when given before the emergence of nephritis in NZB/W F1 mice, and the combination of TACI-Ig and CTLA4Ig can even reverse established nephritis in this model ([ 26] and M Ramanujam and A Davidson, unpublished data).
Differences in the categorical sociodemographic variables between the IG and CG groups were analysed using the chi-square test or Fisher's exact test.
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