With the recent unraveling of the human genome, scientists are cataloging hundreds of thousands of differences in the genetic makeup of different individuals.
There are notable differences in the genetic architecture for different cancer types, with a greater contribution of common variants for prostate cancer.
Some SNPs also showed smaller p-values for DNA measurements (Figure 4B, green bars, labeled as gDNA), reflecting DNA differences in the genetic background of different individuals.
Differences in the genetic architecture of individuals may have affected determinant pathways in different ways.
It is thus likely that the differences in the genetic background of these populations mean that other genes or different variants are underlying the disease.
Because of individual differences in the genetic machinery that regulates stress response, experts say, many people manage their distress despite awful childhoods.
One avenue is the need to determine the importance of seemingly minor differences in the genetic maps of the SARS viruses isolated from the animals in the market in Guangdong Province and those found in humans there and elsewhere.
So he compared DNA samples from all of them, looking for small differences in the genetic material to tell them apart -- a technique akin to the DNA fingerprinting used by crime laboratories.
Mr. Holden, 47, has been the chairman and chief executive of the SNP Consortium, which has been searching for differences in the genetic code among individuals that determine traits such as eye color or susceptibility to certain diseases.
Most observed geographic differences probably result from environmental or cultural influences rather than from differences in the genetic makeup of separate populations.
Large-scale genetic studies have revealed male/female differences in the genetic architecture of adipose tissue amount and anatomical distribution.
