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To test for differences in the attrition rates between the 1st and 3rd vaccinations between the invervention and control groups the χ test will be used.
Of the patients lost to follow-up, 54 (47 %) were on ART; there were no differences in the attrition factors (died, lost, and changed care facility) between patients on ART and those not on ART.
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However, there are differences in the patterns of attrition rates by cadre.
However, there were marked differences in the patterns of attrition rates by HRH cadre.
Longitudinal weights were also applied to account for individual differences in the likelihood of attrition and consent to data linkage.
The mean absolute difference in the actual attrition rate and the expected was 8% with a range of 0.3 31%.
L'abbe type plots created in R (version 2.0.2) were used to represent the difference in the relative attrition among the trials with 95% confidence areas and weights derived from the random effects model.
L'abbe type plots and Forest plots created in R (version 2.0.2) were used to represent the difference in the relative attrition among the trials with 95% confidence areas and weights derived from the random effects model.
Although using state-of-the-art methods for imputing missing data provided us with the best estimation of real data, also correcting for differences in study attrition in the intervention and control group, we should acknowledge that having "true" data are preferable in any case.
Further, to establish whether participant attrition resulted in any meaningful differences between the attrition and test groups, between-groups comparisons will be conducted.
In conclusion, this study provides evidence that the gender-specific differences in telomere attrition depend on factors leading, in the female, to enhanced repair/recombination processes in the lymphocytes (visible by EEE) and, finally, to longer telomeres (evident by greater skewness and kurtosis of the female histogram).
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