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On the other hand, it may be questionable to compare enzyme activities measured in different laboratories, as there may be differences in the analytical methods.
These differences in the analytical approaches might explain different results.
There were many differences in the analytical approaches adopted by the different studies: while some compared the results of the intervention with the situation at baseline, and some compared the results between groups pre- and post-intervention, others focused exclusively on the position post-intervention.
The discrepancy between the dot blot and ELISA results may be due to differences in the analytical techniques.
Inconsistencies across studies might be due to differences in the analytical methods used or to narrow geographic sampling [12], [13].
Both, the type of patients selected as well as the differences in the analytical procedures might be greatly influencing the results.
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Therefore, the difference in the analytical method can contribute to the observed differences.
This difference in the analytical methods made our statistical estimates more conservative, but also more robust.
The difference between the present study and the previous one is a difference in the analytical approach.
However, to highlight the differences in the underlying analytical methods in these three fusion-detection tools, we briefly describe each of the approaches and direct readers to bibliography [ 11– 13] for complete details.
To account for this difference, Θ in the analytical approximations needs to be calculated on the basis of this effective size; i.e., Θ = 4 N e u.
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