Exact(3)
Conversely, it cannot be ruled out that detailed study of reactions catalyzed by enzymes that are currently assigned the same EC number reveals differences in substrates, cofactors or mechanisms that will eventually justify their classification to different EC nodes.
Whether the differences in the strengths of cellobiose inhibition reflect the differences in substrates or the methods used for the measurement of inhibition is not known.
This suggests that despite differences in substrates and reactions, the arginine is essential to maintain the electronic and catalytic requirements fundamental to catalysis in all members of the superfamily.
Similar(57)
Furthermore, the ar/R selectivity filters are distinctly different, suggesting differences in substrate specificity and hence physiological function.
Involvement of these proteins in two different cellular systems and differences in substrate specificity among family members make them interesting candidates for in silico comparative analyses.
However, the substrate-binding pockets differ significantly explaining the differences in substrate specificity between the two enzymes and the failure of ACE inhibitors to bind to and inhibit ACE2 [ 7, 14].
In these cases, different cluster memberships correlate with differences in substrate or stereochemical specificity and differential conservation of residues involved in substrate selectivity.
The distinct roles of CnAα and CnAβ in different tissues may be due to the differences in substrate selection (Perrino et al. 2002).
This prediction necessitates a large family of related sugar transporters, with differing tissue expression patterns, and importantly subtle differences in substrate affinity between transporters.
Major differences in substrate composition and H2 yield using different pretreatment methods were demonstrated.
Therefore, differences in substrate conversion in vivo are mainly based on different sub-cellular localization within expressing cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com