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Inconsistent serotyping results have been reported for other hybrids (10, 15 ) and may result from differences in specificity and potency among different batches of factor serum.
Our results show that the previously observed differences are largely attributable to experimental variation and different methods used rather than actual differences in specificity.
We used the data from trainees who handed in three or more forms to examine possible differences in specificity of comments of different trainee-trainer pairs.
Because of the differences between trainee-trainer pairs in the number of completed forms (range 1 23), we wanted to explore possible differences in specificity between comments of different trainee-trainer pairs.
It remains to be determined if these differences in specificity could account for the different behaviour observed for these two compounds in the BaFiso assay.
The differences in specificity were statistically significant in keeping with the tumour-specific nature of FC uptake compared with relatively non-specific bone uptake of NaF.
The time frame for symptom duration was different across the scales, and this may have affected differences in specificity and sensitivity.
The fact that this cluster apparently encodes several endoxylanases and auxiliary enzymes, such as an exo-acting glucuronidase, might explain why secondary screening on different structurally and chemically-distinct heteroxylans failed to reveal differences in specificity between the clones.
Thus, A2/Melan-A tetramer binding is highly cross-specific and does not discriminate between the very fine differences in specificity and affinity depending on vaccination with analog versus native antigen.
Differences in specificity in this protein family arise from relatively small differences in amino acid sequence.
Crystal structures of these sialosides in complex with SnD1 suggest explanations for the differences in specificity and affinity, providing further ideas for compound design of physiological and potentially therapeutic relevance.
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