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Molecular modelling revealed differences in shapes of representative molecules in series 1 and 2 which may contribute to the variation in cytotoxic potencies.
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Modified and redrawn from Wayne (1986) Fig. 5 The large differences in shape of the skull between three different breeds of dogs, shown in longitudinal section: the "most" paedomorphic at the top, the "most" peramorphic at the bottom.
The differences in shape of the substrate binding pocket could explain the different substrate preference of the two enzymes.
The slight differences in shape of the resulting prions would alter their biochemistry enough to produce the distinct sets of symptoms that accompany different strains.An extraordinary hypothesis, you might think.
In this comparison, the experimental data for energy distributions of BS photons are found to be in reasonable agreement while they are found to have noticeable differences in shape of angular distributions.
In comparisons of this sort the differences in shape of the curves may be important.
The heterozygous samples are identified by differences in shape of the melting curve.
Uncertainties that could compromise the TEF concept were also reviewed, including nonadditive interactions, differences in shape of the dose-response curve, and species responsiveness.
Having observed these differences in shape of early fitness landscapes for fit and unfit runs, we wanted to know if the future fit lineages capitalized on the subtle differences in the landscape immediately, in other words, if future fit runs are fitter from the start.
While these structural differences are functionally significant in nature, difference in shapes of the two sterol skeletons was not commented on by the authors.
If you look at the two graphs below you can see the difference in shape of the Lib Dem (yellow) lines.
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CEO of Professional Science Editing for Scientists @ prosciediting.com