Possible explanations for these conflicting findings include methodological issues, such as different hippocampal boundary definitions, or differences in image acquisition such as our use of 3T MRI, which offers improved image resolution.
These differences in CTC detection rate in early BC could be attributed to the Poisson distribution of rare events [ 60], to differences in patient populations, sampling time points, blood volume analyzed, the use or not of ficoll enrichment before processing with CellSearch®, and differences in image interpretation between different labs.
The variability between different areas was not due to differences in image signal caused by differences in the size, orientation, or stability of the deposited gold particles.
To avoid differences in image quality caused by different equipment vendors, only MR images obtained with 1.5-T systems were included in our study, which limited the number of patients considered for inclusion in our analysis to 93.
In the biological and the bileaflet group, no significant differences in image quality scores were present for the different PHV manufacturers.
As will be described later in the results section, this also makes it possible to employ regression analyses to measure the extent to which variations in BOLD (blood oxygen level dependent) response between different pairs of conditions can be accounted for by low-level differences in image structure between those conditions.
Interestingly, their study showed no significant differences in image quality when using their own algorithm, whereas image quality was different between images reconstructed with the vendors' reconstruction software.
Also it is robust to differences in image illumination and retinal anomalies.
It is made difficult by the inherent complexity of fine 3D anatomy, the natural variability between patients, and differences in image quality.
These measures must take into account individual differences in image processing, phosphene distribution and rehabilitation programs that may be required to optimize implant functionality.
None of the available tools for VE was able to show all anatomical structures, and there were significant differences in image quality.
