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This difference might be due in part to differences in enrolment criteria.
There were no differences in enrolment PSA levels (ANOVA, P=0.5834).
Comparison is limited, however, by differences in enrolment criteria (larger lesions in our study), definition and timing of study endpoints.
Among premenopausal women, the median age at baseline varied substantially across countries due to differences in enrolment protocols between the EPIC centres.
Most of the age effects are, presumably, largely biological, however the model also adjusts for potential differences in age distributions between breeds that might be due to differences in enrolment in insurance or other factors.
These differences in enrolment and testing procedures as well as the low proportion of patients tested for tuberculosis may have introduced potential selection bias in the population included in the study.
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The gender gap refers to the difference in enrolment between boys and girls.
This difference in enrolment might have contributed to the difference in the prevalence.
There was no statistically significant difference in enrolment between males and females (52.2% vs 47.8%, 99% CI p=0.016).
The only significant difference in enrolment rates by sex was in the age group 18 64, where the enrolment rate in women (95.2% CI 94.7 95.7) was higher than that in men (91.1% CI 90.0 92.2).
Further, it was proposed in this previous work that some of the differences geographically in enrolment patterns could be attributed to social networks and 'word of mouth' encouragement to sign up for the NHIS.
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