Such differences in effectiveness and side effects are not unusual in medicine and psychiatry, and they are not played down in a new book called "Shock," which Mrs. Dukakis wrote with Larry Tye, a former Boston Globe reporter.
There were no significant differences in effectiveness between different SSRIs, which confirmed the findings of Gartlehner et al. [ 33].
This suggests that the heterogeneity in the results of these trials cannot be accounted for by differences in effectiveness for different types of patient.
Or, the smaller effect may reflect differences in effectiveness of periodontal treatment delivered in experimental trials compared with periodontal care provided in the community.
Only differences in GI and CV adverse event rates were modelled, with no consideration of the costs arising from any possible differences in effectiveness of the different treatments.
Third, our analyses took into account actual differences in effectiveness between individual statins at different doses, and investigated intervention effect sizes.
This study concluded no differences in effectiveness were induced by different starting points of radiation therapy until 4 days postoperatively.
The study intervention was a computer-assisted comparison of six different graphic communication formats for displaying the differences in effectiveness of two hypothetical cancer screening programs.
However, as Figures 4 and 5 show, these differences in recommendations do often not reflect differences in effectiveness or harms between the different tests [ 49, 62].
Although observational studies are subject to bias, we do not believe that this can explain the substantial differences in effectiveness that we observed across different age groups.
However, research into differences in effectiveness of the intervention between groups of patients with different characteristics (e.g. differences in personality and demographic and medical characteristics) is scarce.
