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However, sequence analysis of DBD sequences of Drosophila and human revealed substantial differences in conservation of orthologous TF DBD pairs both between and within different TF families, suggesting that some divergence of TF binding specificity could have occurred.
Differences in conservation of genes, gene order, and protein sequences are highlighted because they potentially explain the extreme resistance phenotype of B. pumilus.
The differences in conservation of edges were highly statistically significant.
From Figure 1, we can easily note the differences in conservation of the bHLH domain between the Kingdoms, especially in the basic region.
Despite minor differences in conservation of internal organs and skin/soft tissues, all specimens in this case showed excellent conservation and 3(d)).
How unusual this is, is shown in Additional file 7: Text S4b, which highlights the differences in conservation of (presumed) peptide binding residues among various categories of vertebrate MHCI sequences.
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This difference in conservation of the protein sequence suggests that CTU2-type proteins have undergone a stronger divergent evolution than CTU1-type proteins.
We next evaluated the MCS value for each heptamer, which essentially represents the difference in conservation of a heptamer from the expected conservation of a random heptamer (see Methods).
As can be seen in the controls of Figs 5, 6, 7, the presence of an intron makes a difference both in conservation of phase and overall sequence.
The study of diverse criteria may allow for a more precise assessment of the causes of differences in conservation status among populations of a single species.
These differences in conservation were characteristic of all highly discerning sites shared by CVA and SWDA.
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