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Such maps can be subjected to statistical tests to detect groupwise differences in centrality between experimental states.
We also investigated social differentiation (the coefficient of variation of edge weights) to determine whether differences in centrality arose because CORT birds associated more/less equally with conspecifics than control birds.
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However, the plots also indicate the enormous sensitivity of the degree centrality to the threshold level, as significant differences in the centrality values are observed between different thresholds.
But this measure does not account for differences in the centrality of one's friends.
In the nonresponder group, among whom exenatide did not decrease energy intake, there were no differences in eigenvector centrality in the hypothalamic region between exenatide and placebo condition.
In the nonresponder group, we did not obtain significant differences in eigenvector centrality (Fig. 4 C – E ).
We did not obtain significant differences in eigenvector centrality in our region of interest in either of the two groups for rating of nonfood pictures or looking at the fixation cross.
We constructed a human protein interaction network using a modified version of CRG interactome [ 15] and investigated for differences in four different centrality measures namely degree, closeness, betweenness and eccentricity between specific and shared genes.
The difference in global centrality between SZGenes and the other four gene sets was even stronger than that in characteristic shortest-path distances, e.g., the P values by the same test ranged from <2.2×10−16 to 2.7×10−4.
In general, there was a weak difference in the centrality scores between the genes of selection and nonselection.
In this sense, considering that in our sample group differences were more pronounced in centrality than in dissociation, we estimate that the association between these two variables occurs only up to some point, decreasing interaction as other factors come into play, such as higher posttraumatic symptoms and more memory rehearsal.
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