Sentence examples for differences in biodistribution of from inspiring English sources
Differences in biodistribution of 89Zr-labelled-RG7356 were observed for patients in the different dose cohorts.
Exendin-3 and exendin-4 differ in two amino acids (positions 2 and 3) located in the region of the peptide that is involved in internalization of the receptor ligand complex, which might lead to differences in biodistribution of these peptides.
The main difference in biodistribution of the studied Ga-siderophores was in the significantly higher (P < 0.05) intestinal accumulation (see also liver values in Online Resource 2) of Ga-FOXE as compared to that of Ga-TAFC (4.6 ± 1.42 %ID/g at 30 min and 2.4 ± 0.85 %ID/g at 90 min for Ga-FOXE vs. 1.7 ± 1.04 %ID/g at 30 min and 1.0 ± 0.26 %ID/g at 90 min for Ga-TAFC).
However, differences in biodistribution suggested advantages of [F]FETA over [F]FMISO because [F]FETA appeared to be less metabolized in vivo than [F]FMISO [ 50].
The present review was conceived for describing the differences in biodistribution and diagnostic performance of two types of 18 F-radiolabeled choline for positron emission tomography (PET) imaging in prostate cancer (PCa), such as fluoromethylcholine (FCH) and fluoroethylcholine (FEC).
The higher effective doses of the radioiodines can be attributed to differences in biodistribution secondary to (1) different affinity of iodine for NIS transporters; (2) organification of iodine within thyroid, incorporation into thyroid hormone molecules, and subsequent redistribution of these metabolites; and/or (3) higher urinary excretion of 18F-TFB and 99mTc-TcO4−.
This observation is also in agreement with the study of Illidge et al. [ 22].> Differences in biodistribution between In-mAb and Y-mAb conjugates have been observed before in vivo in tumour-bearing mice and in cancer patients [ 23– 25].
No significant differences in the biodistribution of both conjugates were found.
To correct for differences in biodistribution, we calculated paired absolute differences between healthy control joints and OA-induced joints for all untreated rats and TA-treated animals.
The increase of fluorescence in liver most probably indicates a difference in the biodistribution of pHLIP-FIREs compared to pHLIP-T.
To provide a comprehensive basis for nevertheless observed slight differences in tracer biodistribution and dosimetry, the characteristics of [68Ga]HA-DOTATATE were investigated in a detailed preclinical study.
