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There were no differences in antibiotics considered to be "high-risk" for causing CDI between the rCDI and non-rCDI groups.
The wastewater concentrations among the different swine feedlots varied by about two orders of magnitude, which could be related to differences in antibiotics usage and operational scales of the swine feedlots.
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Differences in antibiotic susceptibility among different groups were statistically analyzed by the Fisher exact test.
The different resistance patterns in different geographical regions may be related to differences in antibiotic (aminoglycoside) treatment regimens.
Since there were differences in antibiotic consumption during the different years of the study, we also adjusted for the year.
Some studies only assessed appropriate empiric therapy for MRSA, some included all sterile sites of infection and all studies were from geographically diverse areas which may exhibit differences in antibiotic prescribing, antibiotic resistance trends and differing patient populations.
Related microbial genetic architecture may account for similarities in disease severity despite differences in antibiotic susceptibility.
All strains carried KPC-3, OXA-9 and different TEM and SHV β-lactamases, but none carried the intrinsically avibactam-resistant class B metallo-β-lactamases. No obvious differences in antibiotic resistance genes were observed.
The authors speculated that differences in antibiotic penetration could be attributable to impaired blood flow.
Many other parameters that are often claimed to be associated with better or worse outcome (like differences in antibiotic therapy) did not correlate with outcome.
These differences in structure can produce differences in antibiotic susceptibility; for instance, vancomycin can kill only gram-positive bacteria and is ineffective against gram-negative pathogens, such as Haemophilus influenzae or Pseudomonas aeruginosa.
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