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These results indicate that the levels of the proteins are not constant and may be controlled in a tissue-specific manner, which may contribute to differences in alternative splicing between different cells.
We can conclude that the two different genotypes showed more marked differences in alternative splicing than in change in the level of gene expression.
Differences in alternative splicing have also been described between different ecotypes of Arabidopsis[ 56], giving support to the argument that changes in splicing may contribute to the evolutionary adaptation process.
In addition, differences in alternative splicing could affect sexual dimorphism at the mRNA level, as most of the genes associated with the spliceosome were up-regulated in MFA [22], [23].
The latter case may reflect species specific differences in alternative splicing.
Overall these data indicate that to better understand the molecular bases of phenotypic traits we should also consider the differences in alternative splicing.
Similar(42)
However, we found no significant difference in alternative splicing between N-deficient samples and controls.
However, we saw no significant difference in alternative splicing between N-sufficient and -deficient conditions.
However, when analyzing known splicing events, 11 of 13 exons were found to have a mean difference in alternative splicing scores between the paired samples according to expectation.
To compare the difference in alternative splicing between maize and teosinte, the AS level was defined as the average number of AS events per gene within a species.
Of 13 exons known to be alternatively spliced between CRC and normal colonic mucosa (indicated with exon array probe set IDs in Table S2 in Additional file 2), 11 showed a mean difference in alternative splicing scores between the paired samples according to expectation.
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